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They are engineered molecules designed for this exact purpose, modified to resist enzymatic breakdown and maintain activity for days or even weeks

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Polyamines (spermidine, putrescine) are responsible for the regulation of immune responses and DNA repair

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Summary Keywords blood-brain barrier, nanomaterials, Alzheimers disease, neurodegenerative diseases, amyloid clearance, genetic targeting Citation Sousa JA, Bernardes C, Bernardo-Castro S, Lino M, Albino I, Ferreira L, Brs J, Guerreiro R, Tbuas-Pereira M, Baldeiras I, Santana I and Sargento-Freitas J (2023) Reconsidering the role of blood-brain barrier in Alzheimers disease: From delivery to target

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