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Many patients benefit from combining metformin's insulin-sensitivity effects with semaglutide's appetite suppression and glucose regulation

They remain contraindicated in patients with a personal or family history of MTC or MEN2

doi: 10.1056/NEJMoa1611925 8 WiviottSDRazIBonacaMPMosenzonOKatoETCahnAet al

PIONEER 7 provides data supporting oral semaglutide use as add-on to background oral glucose-lowering agents to improve glycemic control

Your blood pressure would go up

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