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But many patients with diabetes also take GLP-1 agonists to support weight loss, as weight loss itself can improve diabetes outcomes

Understanding how that information is handled is a non-negotiable part of your evaluation

Among AOMs, prescribing increased in March 2025 compared to December 2024 (+17.01%)

Evidence among individuals overweight/obesity without diabetes Larger BP reductions have been observed in RCTs evaluating GLP-1 RAs for weight management among individuals with overweight or obesity without diabetes (Table 2)

Pharmacologic obesity treatment is most effective when integrated into a structured, medically supervised program

Summary: GLP-1 receptor agonists may reduce inflammation by decreasing pro-inflammatory cytokines, modulating immune signalling pathways, and indirectly through weight loss and improved metabolic health