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Evidence for separate roles Several lines of evidence support the notion of distinct roles for peripheral and central GLP-1 in appetite regulation: Differential breakdown: Peripheral GLP-1 has a very short half-life in the blood (around two minutes) due to enzymatic degradation

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Esto no es apropiado para todos los pacientes

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Grandjean J, Schroeter A, Batata I, Rudin M

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Shortness of breath, or dyspnea, is not listed as a common or characteristic adverse effect of GLP-1 receptor agonists in FDA-approved prescribing information

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Gut Microbes 13, 120

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This is one of the most important Australia-specific warnings right now

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