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43 A similar trend towards a higher risk of unfavourable outcomes was observed in the post hoc analysis of the FIGHT trial

13.Pigsborg K, Kalea AZ, De Dominicis S, Magkos F

The titration schedule significantly impacts initial tolerance and should be individualized

The SURPASS-1 trial demonstrated significant improvements in glycemic control and substantial reductions in body weight with all three doses of tirzepatide (5 mg, 10 mg, or 15 mg) compared to placebo over a 40-week period

Health system challenges, particularly in low-resource settings, include limited access to alternative therapies, lack of standardized guidelines, and sociocultural barriers to contraceptive use and pregnancy planning

And the storyinteresting here, people think about the long-acting as convenience, but actually the long-acting gave us a flatter, steadier drug profile so that the side effects were less bothersome