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Improve Sleep (Even If Its Not Perfect) Sleep deprivation lowers GLP-1 and increases hunger hormones like ghrelin

[DOI] [PubMed] [Google Scholar] 171.Nian M, Gu J, Irwin DM, Drucker DJ

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doi: 10.1111/apt.17925

A 39-amino-acid peptide with a fatty diacid moiety attached for half-life extension is harder to synthesize correctly than shorter, simpler peptides

A subsequent systematic review and meta-analysis found that GLP-1RA use was associated with a decrease in steroid use, reduced need for surgery and fewer hospitalizations, although only nine studies were included and there was significant heterogeneity between the groups included so the results should be interpreted cautiously
