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Safety, tolerability, and clinical effects of ZP8396, a novel long-acting amylin analogA single ascending dose trial

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Therapeutic potential for the treatment of obesity Following the cloning of the H3R in 1999 (58), numerous ligands were developed to manipulate the function of the receptor, and the H3R was subsequently proposed as a potential therapeutic target for the treatment of obesity (81, 116, 181, 182)

Amyotroph Lateral Scler 13:418429 Sukhanov S, Higashi Y, Shai SY, Vaughn C, Mohler J, Li Y, Song YH, Titterington J, Delafontaine P (2007) IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice