surmount-4 tirzepatide withdrawal weight regain for the Maintenance of Body Reduction: Rationale, Design, and Baseline Characteristics of SURMOUNT‐MAINTAIN - Horn - 2025 - Obesity ❗️SURMOUNT-4 Maintenance effects of Tirzepatide

I have been on the synergy diet for a couple of months now and have been losing weight each week

So if you handled semaglutide well, there's a good chance you'll handle tirzepatide well too, especially with the slow dose escalation

Medically reviewed by Dr

Efficacy depends on dose escalation and individual metabolic factors, not whether the medication is brand-name or compounded

Last reviewed: June 17, 2026 Last updated: June 17, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

I told my friend: Neither option is inherently good or bad. Its more about what youre comfortable with