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Researchers randomized 322 people to 80 mg of resmetirom daily, 323 to 100 mg daily, and 321 to placebo

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Additionally, plasma AST, ALT, IP-10, MIP-1, and sICAM-1 all decreased with treatment

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as illustrated in Figure 3C, the protein levels of ABCA1 were significantly increased by PARP-1 knockdown or PARP-1 inhibitor 3-AB, compared with those in the control or si-NC (negative control) group