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For the efficacy estimand, the LSM change in HbA1c from baseline at week 52 as the primary endpoint was 2.24%, 2.43%, and 2.58% with tirzepatide 5, 10, and 15 mg, respectively, versus 1.44% with insulin glargine
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doi: 10.1089/dia.2014.0188
Many researchers also feel that obesity is a chronic condition and that long-term treatment is recommended
Mayo Clinic Diet
10.1080/19490976.2023.2274124 109 WangW.MeiA.QianH.LiD.XuH.ChenJ.et al (2023b)
