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Among them, toxin A primarily affects the intestinal epithelium and can cause cytoskeletal actin disassembly via glycosylation of small GTPases in epithelial cells

The peptide might cross the blood-brain barrier and activate GLP-1 receptors in key hypothalamus regions

doi: 10.1089/dia.2011.0050 90 BushMAMatthewsJEDe BoeverEHDobbinsRLHodgeRJWalkerSEet al

Haddad PM
