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It was soon demonstrated that leaks in the blood barrier notably in the area postrema, the subfornical organ and the median eminence would not only allow entry of GLP-1 into these regions of the brain (87), but there was also dense receptor expression at these sites suggesting peripheral GLP-1 might also have actions on the brain (80), and in 1998 it was demonstrated that peripheral intravenous infusions of physiological amounts of GLP-1 would lead to decreased appetite and inhibition of food intake (88)

doi: 10.1080/10543406.2022.2162066

During routine appointments, discuss all over-the-counter products and supplements you are using, including fibre supplements

More serious but less common risks include pancreatitis, gallbladder problems, kidney issues and, based on animal studies, a theoretical risk of thyroid C-cell tumours

circ0030568, circular RNA, 0030568

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