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Despite these challenges, the eGFR slope has emerged as a clinically meaningful outcome, with evidence indicating a robust renoprotective effect from the combined use of GLP1-RA and SGLT2i

Its about being able to provide more comprehensive, integrated care for the patients I already see

However, other cells, primarily including muscle cells and adipose tissue, rely heavily on the insulin hormone to take up glucose

With proper training and protein intake, muscle loss can be limited to 5-15% of total weight loss

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Notably, the clinical application of GLP-1RAs has gradually expanded beyond its original scope