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This is to avoid a potentially dangerous drop in blood sugar

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[11] Yale School of Medicine

A meta-analysis showed no statistically significant difference in efficacy between the two formulations at week 26, despite the numerically higher HbA1c response and body weight with sc semaglutide [59, 60]
101 Interestingly, their effects on markers of cardiovascular risk may be different than those of other weight loss diets

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