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moderate renal impairment (eGFR 30-45 ml/min) has been observed to increase plasma levels of sitagliptin 2-fold, and severe renal impairment can increase plasma levels 4-fold

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Ziel der Arbeit Es soll ein berblick ber spezielle in Entwicklung befindliche Therapien zur Behandlung von Adipositas und Diabetes gegeben werden