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Child Health 30 , 182185 (1994)

10.1517/14656566.2013.824966 [DOI] [PubMed] [Google Scholar] 22.Scheen AJ

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Notably, given that SGLT-2 is expressed in the brain, which is consistent located with enhanced cFos expression induced by SGLT-2is, we hypothesize that SGLT-2is may cross the BBB via receptor-mediated transcytosis

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While clinical trials have demonstrated impressive weight loss outcomes, those results were achieved in environments where patients received significant behavioral support alongside the medication