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Understanding how these medications interact is essential because both can affect your metabolism, appetite, and gastrointestinal function in ways that matter to your success

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From a total of 17,292 patients, 6,426 unique patients were identified to have risk factors for NAION, and 307 were prescribed and dispensed GLP-1R agonists

The SELECT cardiovascular outcomes trial further demonstrated a 20% reduction in major adverse cardiovascular events in overweight and obese adults (Lincoff et al., 2023)

June 2025: The European Medicines Agencys (EMAs) safety committee concluded that NAION is a very rare potential side effect of semaglutide medicines, like Wegovy