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Description
In the hypothalamus, the 5-HT1B receptors are expressed by the NPY/AgRP neurons and their activation inhibits the release of GABA, thus disinhibiting the anorexigenic system, inducing appetite suppression (Figure 1)

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Mounjaro and Ozempic are not indicated for weight loss

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Proper injection technique is crucial for optimal absorption and to minimize injection site reactions
