tirzepatide itchy scalp GLP1 hope (Tirzepatide) : r/TelogenEffluvium Does Mounjaro(Tirzepatide) Cause Hair Loss?:
Description
Activation of the GLP-1R stimulates the PI3K/Akt/mTOR pathway, which in turn upregulates the expression of antioxidant enzymes and reduces ROS production
Nausea was more frequent with tirzepatide vs placebo, especially with tirzepatide 15 mg (OR 5.60 [95% CI 3.12, 10.06]), associated with higher incidence of vomiting (OR 5.50 [95% CI 2.40, 12.59]) and diarrhoea (OR 3.31 [95% CI 1.40, 7.85])
Maintain adequate hydration, especially if experiencing gastrointestinal side effects, to reduce the risk of acute kidney injury
No day reduces gastrointestinal side effects
Users who experience middle-of-night awakenings with hunger pangs despite eating adequate calories during the day may benefit from a small protein-rich snack 2-3 hours before bed
FDA-approved versions remain the first-line option when available
