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Cost estimates: Industry data suggest cold chain logistics adds $8-15 per patient per dose for subcutaneous biologics and $20-50 per dose for IV-administered hospital biologics, before accounting for the cost of temperature monitoring equipment and qualified cold-chain personnel

UK Government and NHS guidance recommends that most adults consider a daily supplement of 10 micrograms (400 IU) of vitamin D, particularly during autumn and winter months when sunlight exposure is limited

Questions remain regarding muscle loss, nutritional adequacy, long-term neurological effects, and what happens when treatment is stopped

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Indeed, preclinical models have shown that GLP-1 can promote synaptic formation, neurogenesis and neuroprotection, and may reduce neuroinflammation [154156]
