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Another potential advantage of this combination is mitigation of insulin-associated weight gain when used in combination with a GLP-1 RA

doi: 10.1007/s12020-025-04206-x

(The other active ingredient in Qsymia is phentermine.) To learn how Qsymia compares with Topamax for weight loss, talk with your doctor

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Research in Diabetes, Obesity and Metabolism (2023) showed that patients off GLP-1 therapy regained an average of 7 pounds per month during the first year, even with maintained diet and exercise

Microneedle-based intradermal versus subcutaneous administration of regular human insulin or insulin lispro: pharmacokinetics and postprandial glycemic excursions in patients with type 1 diabetes