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Therefore, it is likely that the effect of central GLP-1R blockade on bodyweight is due to disrupting the action of CNS-derived rather than peripheral GLP-1

Psychiatric exclusion criteria in obesity and diabetes clinical trials: a missed opportunity

For patients first prescribed an AOM in June 2025, 46.8% filled a GLP-1 RA within 60 days

5 Here we summarized the complex mechanisms of GLP-1RAs and their latest advancements in treating various diseases, such as musculoskeletal inflammation, obesity, cardiovascular diseases, NAFLD, neurodegenerative diseases, and various cancers

2024;166:S-283

Your physician recommends the best option
