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View Semaglutide Tirzepatide A GLP-1/GIP option commonly associated with Mounjaro and Zepbound
Tirzepatide versus Semaglutide once Weekly in patients with type 2 diabetes

Current estimates indicate that more than 20% of adolescents in the United States are affected by obesity, with similar trends observed worldwide

How These Results Compare to Other Weight Loss Medicines Retatrutide's 24.2% mean weight loss at 48 weeks exceeds phase 3 data for semaglutide 2.4 mg (~14.9% at 68 weeks) and is comparable to tirzepatide 15 mg (~22.5% at 72 weeks), though no direct head-to-head trials have been conducted

An initial decline in eGFR is common after treatment initiation but typically stabilizes over time, contributing to long-term preservation of kidney function [108]

Retatrutide shows superior fat loss in trials up to 24% total body weight vs 21% with Tirzepatide
