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A few patients, particularly repeat ones, have described health complications

Semaglutide trials (STEP program) reported nausea in approximately 25-35% of participants at therapeutic doses

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Critics of GLP-1 therapies often portray those who use these medications as opting for an easy way out to achieve thinness, perpetuating longstanding biases like those historically associated with bariatric surgery (Heitmann, 2025)

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