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At week 13, significant reductions versus placebo were observed in glycated hemoglobin (HbA1c: 0.87%), body weight (2.54%), systolic blood pressure (SBP: 3.84 mmHg), pulse pressure (3.81 mmHg), high-sensitivity C-reactive protein (hsCRP: 18.08%), and lipid parameters including total cholesterol (7.00%), nonHDL-C (8.02%), and triglycerides (8.15%)

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This review focuses on two prominent dietary strategies whose nutritional profiles may complement semaglutides mechanisms of action: the Mediterranean diet (MD) and very-low-energy ketogenic therapy (VLEKT)
