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Drinking plenty of fluids can maintain and even improve skin elasticity
These studies were deemed to be comparable in terms of their study design, where most studies were double-blind and multinational, with representation from Europe, North America, South America, Asia, Africa and Oceania

That said, animal studies dont always directly apply to us

Other studies have claimed that peripheral GLP-1 might bind to GLP-1R on the vagal afferent neurons, mainly located in portal circulation, and generate electrical signals to the brain, as was demonstrated in vagotomized rodent models in which GLP-1 did not reduce feeding [58,79,80]
Its the reason why people start treatment, and losing weight by itself has its own health benefits

Rotate sites systematically (abdomen at least 2 inches from navel, front/outer thighs, upper arms) to avoid lipohypertrophy [7]
