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8 Therefore, given the increasing burden of lean MASLD in some populations and the benefits of GLP-1RA in weight management, more clinical attention is warranted

Cultures were passaged once a week while maintained at 37 C in a humidified incubator gassed with 5% CO 2

Diabetes Care (2015) 38:22419

injection of 100 nmol kg 1 MK-801 ( n = 8 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 , GLP-1MK-801 ( n = 8 mice), or vehicle (isotonic saline, n = 8 mice) in DIO mice

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