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The activation of THR is known to improve MASH by controlling fat synthesis, regulating fatty acid oxidation, cholesterol metabolism, mitochondrial function, and reducing inflammation and fibrosis
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Studies have shown tirzepatide can have a greater effect on weight loss and A1C levels, but higher doses are also known to be associated with more severe stomach-related side effects like nausea, vomiting and diarrhea
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Moreover, an online support group, myPCOSteam, has shared that some users utilize Saxenda and may have experienced significant weight loss
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