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These include pancreatitis, gallbladder issues, and potential thyroid concerns (semaglutide carries a boxed warning about medullary thyroid carcinoma in animal studies)

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Different from our results, GLP-1/exendin-4 increases GABA A R-mediated tonic currents and GABA A R-mediated spontaneous IPSC frequency through GLP-1R activation in rat hippocampal CA3 pyramidal neurons [14]

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Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions