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This umbrella review synthesizes the evidence for safety and efficacy GLP-1 receptor agonists on multiple outcomes including but not limited to metabolic, cardiovascular and renal outcomes.

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My take: GLP-1RAs may become more than metabolic drugs, but oncology needs prospective cancer-outcome data before calling this prevention

OR2=0.21 [95% CI 0.050.92], P2=3.89102)