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Translational challenges for these agents are also discussed, particularly the need to understand how the timing of treatment may influence outcomes

It acts as a bispecific molecule, combining GLP-1 receptor agonism with GIP receptor antagonism to promote weight loss

These medications, which include Novo Nordisks semaglutide, sold as Ozempic and Wegovy, and Eli Lillys tirzepatide, sold as Zepbound and Mounjaro, are not recommended for use during pregnancy because their safety for the fetus is unknown and animal studies have suggested potential risk

Clinically proven to help patients lose up to 15% of their body weight

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But does spironolactone cause weight gain