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64 These reductions in fat mass, lean body mass, and muscle mass correlate with the degree of body weight reduction and are similar to those documented with other obesity therapies that achieve large weight reductions, such as bariatric surgery and very low-calorie restricted diets

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K(ATP) channels and islet hormone secretion: new insights and controversies

Previous studies have demonstrated that neurogenesis influences emotional regulation in adult mice (Deng et al., 2009), and that enhanced neurogenesis in the hippocampus acts as an antidepressant for increasing serotonin receptor activity (Wang et al., 2008

Bias between mini-G s and -arrestin-2 recruitment was determined similarly to earlier work (Pickford et al ., 2020), by subtracting the log /K values (Kenakin et al ., 2012) for each ligand in each pathway for each assay to determine log /K A (referred to here as LogR)