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Therefore, such background factors should be considered when interpreting the treatment effects across dosage groups

Animals were excluded from an analysis if the handler noted a bad injection of drug and/or glucose or if they lost weight and became ill between experiments

Patients should be provided with clear safety advice , including when to temporarily discontinue SGLT2 inhibitors (during acute illness, dehydration, or 3 days before surgery), recognition of DKA symptoms (nausea, vomiting, abdominal pain, unusual fatigue), and management of genitourinary infections

doi: 10.1113/jphysiol.2005.087510

competing therapies, which is expected to offer collateral cardiovascular benefits