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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Ryan D.H

Balance between on- and off-target effects of the dual GLP1/E agonist, and the concurrence of desensitization at very high doses, might contribute to this phenomenon

Medications like GLP-1s are no longer simple adjuncts to care, they increasingly function as both a substitute and complement to high-margin surgical procedures

In conclusion, this study provides mechanistic evidence to demonstrate the anti-apoptotic and anti-inflammatory effects of GLP-1R activation in chondrocytes, in vivo and in vitro

[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Bierhansl L., Hartung H.-P., Aktas O., Ruck T., Roden M., Meuth S.G

At its core, it's a clever mimic of a natural hormone your body already produces called GLP-1 (glucagon-like peptide-1)