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Evaluating what the research shows about GLP-1 medications and depression and suicidal ideation.

Tackling multiple diseases with a single prescription, making GLP-1s a disruptor in todays medical landscape
The results of the PIONEER-3 trial have now been published in the renowned journal Journal of the American Medical Association (JAMA) and are said to be trend-setting for future therapy of type 2 diabetes.

GLP-1s account for 23% of first line diabetes therapy in 2025 up from 3% in 2021 Since 2019, the American Diabetes Association (ADA) has revised its Standards of Care each year to expand the role of GLP-1 receptor agonists and SGLT2 inhibitors as first-line treatments for T2D2

In todays newsletter: A new study shows that people dont just regain weight after stopping GLP-1 drugs, they see other positive health markers reverse leading to questions about long-term impacts and solutions

In a letter, the FDA said it needs more data to fully understand several possible risks tied to the drug, including heart and liver problems.