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These findings underscore the potential for GLP-1 RAs to offer tailored protection against complex diabetic complications, marking an advancement in personalized medicine for managing diabetes-acute kidney disease.

Some sub-analyses of large clinical trials suggest that GLP-1RA and sodium-glucose cotransporter 2 inhibitor combination therapy may provide more significant reductions in heart failure hospitalization and renal composite events than each alone

Partly through these actions, GLP-1 receptor agonism was shown to reduce cardiovascular disease (CVD) in people with T2D with previous CVD or at high-risk thereof

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