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Clinical evidence from large-scale trials, including SUSTAIN-6, demonstrates that Ozempic does not increase cardiovascular risk and may offer protective benefits for certain high-risk patients

My health was deteriorating fastI had high blood pressure , diabetes , and no energy to even get out of bed
I am losing about 1-2 lbs every 2-3 weeks which is great for me

The American Society for Metabolic and Bariatric Surgery (ASMBS) acknowledges that pharmacotherapy may be appropriate for post-surgical weight regain but emphasizes the importance of comprehensive evaluation, behavioral intervention, and nutritional optimization before medication initiation

Risk of an infeasible or underpowered trial Given the aforementioned logistical, ethical and financial issues, a 2-arm RCT comparing the use of GLP-1 drugs for cancer prevention may not be feasible in the real world

Functional studies are beginning to elucidate the molecular impact of key variants, and the development of high-throughput CRISPR-based assays will accelerate this progress
