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Metformin, on the other hand, has a much smaller effect on weight

In January 2026, a pill version of Wegovy (semaglutide) became available in the U.S after receiving FDA approval in December 2025
Benge says, and Dr

Some of the early concern came from people I respected, including Peter Attia, who flagged lean-mass loss on scans in his own practice
[DOI] [PubMed] 46.Li J, Mooney DJ

According to the nonprofit health policy organization KFF, approximately 12 percent of adults in the United States (more than 31 million Americans) currently use a GLP-1 medication
