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Parenteral delivery systems, including intramuscular, intravenous, and subcutaneous injections, are highly preferred for their rapid onset of action, precise dosing, and high bioavailability
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Arnolds S, Dellweg S, Clair J, Dain MP, Nauck MA, Rave K, Kapitza C

Nature Medicine, 30 (7), 2049-2057

Estrogen can also support more favorable body fat distribution and better insulin sensitivity in some women, which may help with metabolic health, but it should not replace dedicated treatments for blood pressure, blood sugar, or obesity

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