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The term emerged organically from patient reports and clinical observations, not from a single published study

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Nine transporters are discussed, including two apically localized efflux transporters that have significant expression in the intestine: P-gp and breast cancer resistance protein (BCRP)

Options such as Miralax (polyethylene glycol) or magnesium citrate can be used if needed with direction from your healthcare provider

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But new research from Stanford Medicine and international collaborators suggests these widely prescribed drugs may be less effective for some patients because of their genetics