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Description
Patients entered a 2-week, single-blind run-in treatment period on pre-mixed, long-acting, or intermediate-acting insulin, with or without metformin HCl (1500 mg per day)

For women with PCOS, GLP-1 receptor agonists have shown better outcomes compared to metformin, particularly in weight loss and improving insulin resistance

Hernandez AF, Green JB, Janmohamed S, D'Agostino RB, Granger CB, Jones NP, et al

Particular attention was paid to subgroup differences, especially among younger and obese individuals
10.1093/ajcn/82.5.923 28 WatersD

Alternatives for Pregnancy-Safe Support Depending on their clinical profile, options may include: Insulin or metformin for glycemic management Medical nutrition therapy Prenatal physical activity programs More frequent check-ins with OB and primary care And while weight loss is never the goal during pregnancy, we can help patients stay within recommended weight gain guidelines and support their metabolic health through lifestyle modifications and regular monitoring