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Back Thorens, B, Porret, A, Bhler, L, et al (Nov 1993) Cloning and functional expression of the human islet GLP-1 receptor
Physiologically, it can bind to GLP-1 receptor on pancreatic beta cells through endocrine, activate adenylate cyclase, increase intracellular cAMP levels, promote glycolysis and ATP production, and enhance glucose-stimulated insulin secretion
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There are several important clinical considerations when choosing 1 of the 6 currently available GLP-1 receptor agonists for a patient
