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Medical supervision helps: reduce risk of side effects determine appropriate dosing monitor progress ensure safe transition timing Careful planning helps improve comfort and treatment outcomes

Semaglutide, the active ingredient in Wegovy, was being tested as an Alzheimers treatment

DeFronzo RA, Buse JB, Kim T, Burns C, Skare S, Baron A, Fineman M

Cycle guidelines Cycle guidelines Approach Phase 2 reference Duration 48 weeks Review Point Every 4 weeks at each dose step Best For Matches the original NEJM trial structure Approach Phase 3 TRIUMPH reference Duration 68-72 weeks Review Point Every 4 weeks

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Clinical studies show an average of 15% body weight reduction over 15 months when combined with a healthy lifestyle