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Use of expired drugs: patients benefits versus industry interest

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Key Advantages of GLP-1: The Multifaceted Benefits of GLP-1 for Older Adults Weight Management One of the most significant benefits of GLP-1 receptor agonists is their ability to aid in weight loss

13 Given these multiple actions, in pediatric models, GLP-1R activation may directly interfere with metabolic plasticity, cellular differentiation, and tissue remodeling, requiring caution regarding potential off-target effects during growth and development

The results showed that GLP-1 agonists have a favorable safety profile, with most side effects being mild and temporary

Finally, the exclusion of highrisk populations introduces selection bias, and the likelihood of publication bias, whereby studies reporting favourable outcomes are overrepresented, further constrains the interpretability and clinical applicability of the existing literature
