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This loss in fat mass might be what is causing you to feel chills with Ozempic, because your bodys insulation is diminishing, and subsequently your metabolism is changing

Combining them creates a situation where some of these overlap, some cancel each other out, and some amplify each other

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However, if you were a true non-responder to Saxenda (no appetite change, no weight loss despite proper adherence), you might still respond to semaglutide, but response isnt guaranteed