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Ongoing monitoring should include assessment of glycemic control, weight, gastrointestinal tolerability, and renal function, particularly during dose escalation or in patients experiencing significant gastrointestinal adverse effects

Emerging options are becoming available to increase access to gutbrain axis modulation, such as internet-delivered CBT or app-delivered gut hypnosis

Tirzepatide 2.5 mg is a starting dose, not a maintenance dose

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Biofeedback helps to promote a state of relaxation