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Lorcaserin (Belviq ) is currently the only serotonin receptor activating anti-obesity pharmaceutical which is still approved for clinical use

6 ADVERSE REACTIONS The following serious adverse reactions are described below or elsewhere in the prescribing information: Risk of Thyroid C-cell Tumors [see Warnings and Precautions (5.1)] Pancreatitis [see Warnings and Precautions (5.2)] Diabetic Retinopathy Complications [see Warnings and Precautions (5.3)] Hypoglycemia with Concomitant Use of Insulin Secretagogues or Insulin [see Warnings and Precautions (5.5)] Acute Kidney Injury [see Warnings and Precautions (5.6)] Hypersensitivity [see Warnings and Precautions (5.7)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

The lower starting dose helps minimize the risk of side effects, especially gastrointestinal symptoms like nausea or upset stomach

The compounded version would also be legal if a doctor prescribes it to patients who cant afford the brand version

These data provide a potential mechanism by which central GLP-1 receptor stimulation modulates parasympathetic outflow to the heart and increases heart rate