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Oral tirzepatide versus injection comparisons are becoming more relevant as oral tirzepatide formulations enter development

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For weight management , NICE technology appraisal guidance supports semaglutide 2.4 mg (Wegovy) for adults with at least one weight-related comorbidity and a BMI 35 kg/m (or 30 kg/m in exceptional circumstances), as part of a specialist weight management service

However, emerging research reveals a counterintuitive pattern: some people experience a modest rebound in GLP-1 levels during extended fasts as the body prepares for the next meal

The Hospitals segment dominated the market with a share of 44.26% in 2025 owing to high patient volumes, comprehensive diabetes management programs, and access to multidisciplinary healthcare teams