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This enzyme is a zinc-dependent metallopeptidase that is expressed in many different tissues, with especially high expression level in the kidney

Regarding obesity management, coverage for semaglutide may be more limited, as it was originally developed as a diabetes medication

doi: 10.3390/nu13020351 [DOI] [PMC free article] [PubMed] [Google Scholar] 209

This study suggests that GLP-1 drugs may offer protective benefits potentially improving survival and recurrence risk in some female patients with breast cancer whether this is related to weight control, improve cardiovascular health or other mechanisms remains to be studied, said study senior author Bernard F
doi: 10.1038/s41380-022-01792-4
