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The GLP-1s that were originally marketed as a diabetes treatment include semaglutide, brand name Ozempic, liraglutide, brand name Victoza, dulaglutide, brand name Trulicity, and the latest GLP-1 to the market, tirzepitide, brand name Mounjaro, which is a combination GIP/GLP-1

This expanding patient base with unmet medical needs amplifies the demand for innovative and efficient diabetes treatments, positioning Mounjaro favorably in a market shaped by a persistent increase in type 2 diabetes prevalence

American Diabetes Association: New GLP-1 Therapies Enhance Quality of Weight Loss by Improving Muscle Preservation

Importantly, the Sema + -MSTN/-ActA group which had similar body weight reduction but increased lean mass compared to Sema alone also had markedly greater losses in fat mass, almost twice that seen with Sema alone (Fig